The tones and textures were added to these pen and ink mice by using a clipping mask in Adobe Fresco. For the comic that I’ve got in mind, Mouse 1, Row 2, is the one to go for, drawn with Fresco’s ‘watercolor wet spatter’ brush. I want to rather dreary and slightly disconcerting look, like a production of Samuel Beckett’s Waiting for Godot. If it was a Victorian story, I’d go to town with the ‘cross hatch’ from the selection of ‘Comic’ brushes.